Top 250+ Best & Worst Pharmacy Research Topics

Introduction

Finding the right pharmacy research topics is often the biggest challenge for students of B.Pharm, M.Pharm, and PhD programs. Your research topic can shape your academic record, determine your scope for publication, and even influence your future career in the pharmaceutical industry.

Whether your interest lies in formulation science, analytical method development, herbal medicines, or clinical pharmacy, selecting meaningful and up-to-date pharmacy research topics is the first step toward academic success.

This blog presents a powerful and categorized list of 250+ pharmacy research topics, carefully selected from top-performing academic trends, high-scoring projects, and real-world applications. It includes both the best pharmacy research topics that are innovative and publication-worthy, and worst pharmacy research topics that are outdated or too common to impress.

If you’re planning to publish or present, don’t forget to explore the best tools for pharmacy research writing to help with grammar, plagiarism removal, paraphrasing, and citations.

Additionally, for literature-backed topics, databases like the NCBI research database are invaluable sources for previous studies, trials, and verified references to strengthen your pharmacy research topics.

This evergreen and SEO-curated list will help students like you find unique, practical, and high-potential pharmacy research topics in domains like pharmaceutics, chemistry, pharmacovigilance, nutraceuticals, and more.

If you’re still confused about how to draft your proposal, check out this guide on how to write a pharmacy research proposal.

Pharmaceutics

1. Formulation and evaluation of Atenolol multiparticulate drug delivery system
2. Preparation and evaluation of zinc oxide nanoparticles of Saraca asoca leaf extract
3. Preparation and evaluation of microemulsion using a model drug
4. Formulation and evaluation of dispersible tablet of taste-masked Mebeverine
5. Formulation and evaluation of Diltiazem floating tablets
6. Preparation and evaluation of microspheres using a model drug
7. Formulation and evaluation of controlled release multiparticulate drug delivery system of Atenolol
8. Formulation and evaluation of herbal lip balm from lentil and Tagetes patula
9. Preparation and evaluation of oral thin films (OTFs) using a model drug
10. Evaluation of wound healing activity of herbal formulation vs marketed sample
11. Bacteriological evaluation of drinking water samples from different sources
12. Formulation and evaluation of herbal cream
13. Formulation and evaluation of topical gel of methanolic extract of Cyperus rotundus for arthritis
14. Formulation and evaluation of herbal tablet for hypertension
15. Formulation of polyherbal antidiabetic suspension
16. Formulation and evaluation of carrot-beetroot beverages as probiotics
17. Formulation and evaluation of polyherbal hair oil
18. Formulation and evaluation of polyherbal shampoo
19. Evaluation and comparison of antidandruff shampoos
20. Process automation in pharmaceutical industry with reference to tablet manufacturing
21. Formulation and evaluation of herbal gel
22. Use of computers in pharmaceutical formulation development
23. 3D printing in Pharmaceutics: A novel tool for customized drug delivery
24. Formulation and evaluation of herbal tablet for cancer
25. Evaluation of polyherbal antidiabetic suspension
26. Artificial intelligence, robotics, and computational fluid dynamics in pharmaceutics
27. Development of fast-dissolving tablets using co-processed superdisintegrants
28. Development and evaluation of colon-targeted drug delivery systems using natural polymers
29. Preparation and characterization of Jolmitriptan oral integrating agents
30. Floating tablets of Irbesartan for gastro-retentive drug delivery
31. Vildagliptin beads by ionotropic gelation method
32. Formulation and evaluation of oxiconazole emulgel for topical delivery
33. Fluconazole Ocuserts: In vitro & in vivo evaluation
34. Fast dissolving tablets of Pantoprazole sodium using sublimation method
35. Development and validation of novel hydrotropic solubilization method for Mycophenolate Mofetil
36. Starch acetate as rate-controlling matrix for Aceclofenac controlled release
37. Metformin HCl microspheres using ionic gelation technique
38. Absorption enhancement studies of Pantoprazole using various enhancers
39. Development and evaluation of formulation containing anti-TB drugs
40. Vaginal/rectal drug delivery system for HIV prevention
41. Anti-sunburn preparation with silver nanoparticles from Cynodon dactylon
42. Nanocarriers for nose-to-brain drug delivery
43. Extended release pellets for chronotherapy of rheumatoid arthritis
44. Liquid crystal-based drug delivery system
45. Effect of penetration enhancer on Paracetamol release from transdermal patch
46. Methotrexate nanostructured lipid carriers for psoriasis treatment
47. Tacrolimus-loaded liquid crystalline nanoparticles
48. Risedronate sodium nanosponges
49. In situ gel containing metronidazole-loaded liposome for periodontitis
50. Leflunomide-loaded pluronic lecithin organogel for rheumatoid arthritis
51. Hydroalcoholic dissolution media impact on antianginal drug release
52. Raft-forming system for sustained drug delivery of Clopidogrel
53. Luliconazole-loaded niosomal gel for fungal infection
54. Solubility enhancement of Resveratrol by nanocarrier formulation
55. Herbal hair spa kit: Formulation and evaluation

Pharmacognosy

56. Pharmacognostic evaluation of Acacia auriculoformis
57. Phytopharmacology and formulation studies of Rubia cordifolia
58. Herbal drugs in Parkinson’s disease
59. Herbal drugs in Alzheimer’s disease
60. Anthelmintic potential of Acacia auriculiformis pods
61. Phytochemical and blood glucose-lowering effects of Didymocarpus pedicellata extract
62. Anxiolytic potential of Rubia cordifolia acetone extract
63. WHO and AYUSH guidelines for safety monitoring of natural medicines
64. Herbal cream: Formulation and evaluation
65. In-vitro anti-inflammatory activity of Acacia auriculiformis bark
66. Scientific studies on Ficus religiosa
67. Wound healing activity of Bergenia ligulata extract
68. Analgesic potential of Acacia auriculiformis
69. Anti-arthritic activity of Muntingia calabura
70. Cytotoxicity of various Azadirachta indica extracts
71. In-vitro anti-diabetic and anti-inflammatory activity of Syzygium cumini
72. Antiglycation studies on Hibiscus micranthus leaf extract
73. Antioxidant potential of Typha angustata
74. Ethnobotanical survey and scientific validation
75. Natural materials as pharmaceutical excipients
76. Inflammation mitigation mechanism of Bridelia aiya shawii
77. Physicochemical analysis of Ayurvedic marketed formulations
78. HPLC analysis of Guggul post-shodhana process
79. Tribal medicinal formulations: Documentation and validation
80. Quantitative standardization study (RPS)

Pharmaceutical Analysis

81. Hydrotropic solubilization study of selected drugs using UV spectroscopy
82. Method development and validation of Paclitaxel by UV spectrophotometry
83. UV spectrophotometric method development for Zidovudine
84. Method development and validation of Vildagliptin

Biotechnology

85. Antibacterial and antifungal activity of medicinal plants
86. Antimicrobial activity of aqueous extract of cinnamon, coriander, mint, and black cumin

Pharmacology

87. Analgesic activity of clove oil
88. Antianxiety activity of Bauhinia variegata in mice
89. Review on herbal therapies for peptic ulcer
90. Antibacterial potentials of natural product extracts
91. Comparative study of Ashwagandha and Brahmi for anxiolytic activity
92. COVID-19: Current status
93. In vivo anti-infective potential of aqueous plant extracts
94. Ethnomedical exploration of anti-infective plants
95. Plant extract bactericidal activity (Gram +ve and -ve)
96. Fasting effects on glycogen metabolism in rats
97. Self-medication and chronic disease survey
98. In vitro angiogenesis model for phytoconstituents
99. Endocannabinoid ligands in metabolic syndrome
100. Formononetin effects in microvascular diabetic complications
101. Dopamine interactions in neuropsychiatric disorders
102. Triterpenoid evaluation in diabetic animal model
103. Phototherapy effects on neonatal hyperbilirubinemia
104. Traditional herbs from North Maharashtra for psychological disorders
105. Pharmaceutical care in T2DM in civil hospital
106. Antioxidants in diabetic nephropathy
107. Hypolipidemic plant studies from Satpuda
108. HbA1c and metabolic syndrome in hypertensives
109. Risk factors in tribal hypertensive population
110. Valacyclovir UV spectrophotometric method development
111. Malnutrition in tribal children: Prevalence and treatment
112. Artificial animal mannequins as alternatives in education
113. Ghrelin-dopamine interaction in lifestyle diseases
114. AYUSH EMR project: Anti-inflammatory drug evaluation
115. PI3K/AKT/PPAR-gamma pathway in myocardial infarction
116. Pharmacological investigation of Cassine albens
117. Drug discovery using bioinformatics and molecular biology

Quality Assurance (QA) & Regulatory Affairs

118. Validated UV spectrophotometric method for estimation of Valacyclovir in tablet dosage form
119. Formulation development and evaluation of RUTF-based nutraceuticals for severe malnutrition
120. Novel lipid-based nanoformulation of bioactive polyphenols for prophylactic cervical cancer treatment
121. Non-invasive nanoparticles-based buccal drug delivery for oral cancer
122. Design and evaluation of nanoparticulate drug delivery system for poorly water-soluble drugs
123. Software-assisted design and optimization of lipidic nanoparticles to enhance bioavailability
124. Ready-to-use supplementary foods from local medicinal plants to combat child malnutrition
125. FDP: Recent advancements in herbal formulation and ISM drug delivery systems
126. RPS: Design and characterization of floating drug delivery system with bi-phasic release and shelf-life estimation
127. Design of experiments (DoE)-assisted forced degradation studies and impurity profiling
128. Photo-stability study of APIs in dosage forms in presence of photocatalyst
129. Quality by Design (QbD) approach for analytical and bioanalytical method development
130. Application of experimental design in HPLC to reduce cost and improve efficiency
131. Stability-indicating assay method development using HPLC for bulk drugs and formulations
132. Development and validation of stability-indicating analytical methods for new drugs
133. Implementation of quality control parameters in evaluation of vegetable crude drugs
134. Process validation of Pimax tablet
135. Randomised open-label crossover clinical study of Telmisartan bioequivalence
136. Cross-sectional study on awareness and use of Drug Information Centres (DICs) among pharmacists and physicians

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Pharmaceutical Chemistry

137. Synthesis and antimicrobial activity of acetanilide derivatives with aromatic aldehydes
138. Synthesis and evaluation of Schiff’s bases of diphenylcarbazide for antimicrobial potential
139. Schiff base derivatives of substituted phenylhydrazines: synthesis and screening
140. Synthesis and evaluation of thiazolidinones for analgesic activity
141. Synthesis of zinc oxide nanoparticles from Acacia auriculiformis extracts (leaf & fruit)
142. Investigation of Bougainvillea varieties as natural acid-base indicators
143. Synthesis of novel chalcone derivatives from 5-nitrosalicylaldehyde and 4-aminoacetophenone
144. Synthesis of benzylidene acetophenone derivatives
145. Design and synthesis of 2-chloromethylbenzimidazole metal complexes
146. Exploration of thiazolidinone derivatives for analgesic activity
147. Synthesis and screening of azetidinones as potential anticonvulsant agents
148. Design of mutant T790M EGFR-tyrosine kinase inhibitors as anti-cancer agents
149. Bioevaluation of 2-substituted/2,7-disubstituted 5-methoxy indole derivatives
150. Design, synthesis and evaluation of sulphonamide derivatives
151. Review: Derivatization of natural products
152. Review on Ranitidine as a potential cancer-causing agent
153. In silico design and synthesis of N-heterocyclic anti-cancer agents
154. Discovery of quinazolines as Gly-NMDA receptor antagonists using docking studies
155. UPLC and HPTLC-MS analysis of APIs in formulations
156. RP-HPLC analysis and bioanalysis of pharmaceutical drugs
157. Review: Arka Kalpana in Ayurvedic medicine
158. Development and validation of newer analytical methods for simultaneous estimation of gliptins and metformin
159. Analytical method development for miconazole nitrate and eugenol in a synthetic mixture

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Pharmacovigilance, Pharmacoepidemiology, Clinical Pharmacy

A. Adverse Drug Reaction (ADR) & Safety Studies

160. Analysis of ADRs reported for a specific class of drugs
161. Effectiveness evaluation of pharmacovigilance systems in healthcare settings
162. Impact of social media on pharmacovigilance and drug safety reporting
163. Algorithm/tool development for early ADR detection using PV data
164. Comparative analysis of pharmacovigilance regulations in different regions
165. Prospective study of ADRs and their impact on quality of life in psychiatric patients
166. Observational study on cutaneous ADRs with severity scoring in dermatology

B. Clinical Studies & Patient Quality of Life

167. Impact of patient counseling on QoL in type 2 diabetes and hypertension
168. Clinical profile and QoL assessment in patients with chronic liver disease
169. Frailty and comorbidities: QoL correlation in hemodialysis patients
170. Fexofenadine HCl efficacy study in chronic idiopathic urticaria
171. QoL assessment in CKD patients with hypertension and diabetes
172. Observational study in chronic low back pain cases
173. Cognitive impairment prevalence in diabetes, hypertension, or both
174. Risk factors associated with low birth weight in neonates
175. Clinical profile and QoL in migraine patients
176. Psychological burden of vitiligo and clinical severity correlation
177. Cross-sectional study on awareness of novel coronavirus
178. Knowledge, attitude and perception study on pharmacogenomics among pharmacy students
179. Postpartum depression characteristics and pharmacist-led counseling impact
180. QoL and inhaler technique in respiratory disease patients

C. Drug Utilization & Prescription Pattern Studies

181. Drug utilization study in asthma, COPD, renal impairment, epilepsy, anemia, etc.
182. Pattern of discharge prescription medications in CKD patients
183. Pharmacoeconomic burden of asthma in tertiary care hospitals
184. Evaluation of polypharmacy and drug-related problems in type 2 diabetes
185. Drug-food interaction assessment in hospital prescriptions
186. Prescription pattern and adherence of antiepileptic drugs
187. Pharmacoeconomic analysis of HIV/AIDS management in hospital settings
188. Utilization pattern of antidepressants in psychiatric patients
189. Study of insulin therapy perceptions in type 2 diabetes patients
190. Clinical evaluation of contrast-induced nephropathy in cardiology patients
191. Observational study of antiplatelet agent use in cardiology
192. Study on microbial contamination of disinfectants and antiseptics
193. Evaluation of drug use in topical agent-induced skin reactions
194. Evaluation of cutaneous ADRs in dermatology department
195. Knowledge assessment of common drug dosages in Indian population
196. Awareness and practices around disposal of expired/unused medicines

Herbal, Nutraceutical & Advanced Drug Delivery Projects

197. Herbal hair spa kit: formulation and evaluation
198. Leflunomide-loaded pluronic lecithin organogel for rheumatoid arthritis
199. Hydroalcoholic dissolution media effect on extended-release tablet behavior
200. Metronidazole-loaded liposomal in situ gel for periodontitis
201. Formulation and evaluation of Risedronate sodium nanosponges
202. Solubility enhancement of Resveratrol via nanocarriers
203. Tacrolimus-loaded liquid crystalline nanoparticles
204. Aloe vera + omega-3 + CoQ10 in gentamicin-induced nephrotoxicity in rats
205. Silymarin + omega-3 + CoQ10 in paracetamol-induced hepatotoxicity
206. Mosquito coil preparation using orange peel as natural repellent
207. Phytochemical and antimicrobial screening of Mangifera indica and Citrus sinensis
208. Isolation of spoilage microorganisms in banana fruit deterioration
209. Drug formulation and evaluation of raft-forming systems for Clopidogrel
210. Luliconazole-loaded niosomal gel for fungal infections

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Conclusion: Choosing the Right Pharmacy Research Topic

Selecting the right pharmacy research topic is not just about fulfilling academic criteria; it’s about standing out with original ideas and contributing to the scientific community. With this curated list of top 250+ pharmacy research topics, students of B.Pharm, M.Pharm, and PhD programs can explore the best ideas across all major domains.

Avoid outdated themes and go for research topics that are innovative, practically feasible, and offer scope for real-world application. The right pharmacy research topic can lead to publications, awards, internships, and even job offers in R&D, clinical, and regulatory fields.

We hope this list of pharmacy research topics proves helpful in your academic journey. For more such research ideas, writing tools, and pharmacy career content, keep following PharmacyProfessor.com.